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Venlafaxine Brand names:

• Pristiq® Tablets (prolonged launch): 25 mg, 50 mg, 100 mg
• Khedezla® Tablets (prolonged launch): 50 mg, 100 mg
• Desvenlafaxine Tablets (prolonged launch): 25 mg, 50 mg, 100 mg

What is Venlafaxine?

Venlafaxine is an antidepressant medicine that works within the mind. It is authorized for the remedy of main depressive dysfunction (MDD).

Symptoms of despair embrace:

• Depressed temper – feeling unhappy, empty, or tearful
• Feeling nugatory, responsible, hopeless, and helpless
• Loss of curiosity or pleasure in your common actions
• Sleep and eat kind of than common (for most individuals it’s much less)
• Low vitality, bother concentrating, or ideas of demise (suicidal pondering)
• Psychomotor agitation (‘nervous energy’)
• Psychomotor retardation (feeling like you’re transferring and pondering in gradual movement)
• Suicidal ideas or behaviors

What Is Important Information to know about This medicine?

Do not cease taking, even whenever you really feel higher.  With enter from you, your well being care supplier will assess how lengthy you will have to take the drugs. Missing doses of Venlafaxine might improve your threat for relapse in your signs.

Stopping abruptly might end in a number of of the next withdrawal signs:

• irritability
• nausea
• feeling dizzy
• vomiting
• nightmares
• headache
• paresthesia’s (prickling, tingling sensation on the pores and skin)

Depression can also be part of bipolar sickness. People with bipolar dysfunction who take antidepressants could also be in danger for “switching” from despair into mania. Symptoms of mania embrace “high” or irritable temper, very excessive vanity, decreased want for sleep, strain to maintain speaking, racing ideas, being simply distracted, steadily concerned in actions with a big threat for dangerous penalties (for instance, extreme shopping for sprees).

Medical consideration ought to be sought if serotonin syndrome is suspected. Please discuss with severe unintended effects for indicators/signs.

Are There Specific Concerns About Venlafaxine?

If you’re planning on changing into pregnant, notify your well being care supplier to greatest handle your drugs. People residing with MDD who want to turn out to be pregnant face essential choices. Untreated MDD has dangers to the fetus, in addition to the mom. It is essential to debate the dangers and advantages of remedy along with your physician and caregivers. For girls who take antidepressant drugs throughout weeks 13 by way of the tip of their being pregnant (second and third trimesters), there’s a threat that the infant could be born earlier than it’s absolutely developed (earlier than 37 weeks).

Caution is suggested with breastfeeding since venlafaxine does move into breast milk.

What Should I Discuss With My Healthcare Provider Before Taking?

• Symptoms of your situation that trouble you probably the most
• If you’ve gotten ideas of suicide or harming your self
• Medications you’ve gotten taken up to now in your situation, whether or not they had been efficient or induced any antagonistic results
• If you expertise unintended effects out of your drugs, talk about them along with your supplier. Some unintended effects might move with time, however others might require modifications within the medicine.
• Any different psychiatric or medical issues you’ve gotten, together with a historical past of bipolar dysfunction
• All different drugs you’re at present taking (together with over-the-counter merchandise, natural and dietary dietary supplements) and any medicine allergic reactions you’ve gotten
• Other non-medication remedy you’re receiving, reminiscent of speak remedy or substance abuse remedy. Your supplier can clarify how these totally different therapies work with the medicine.
• If you’re pregnant, plan to turn out to be pregnant, or are breastfeeding
• If you drink alcohol or use medication

How Should I Take Venlafaxine?

• Venlafaxine is often taken one time per day with or with out meals.
• Typically sufferers start at a low dose of medication and the dose is elevated slowly over a number of weeks.
• The dose often ranges from 50 mg to 400 mg. Only your healthcare supplier can decide the right dose for you.
• The tablets ought to be swallowed complete. They shouldn’t be chewed, crushed, or damaged.
• If you take venlafaxine, you shouldn’t take different drugs that embrace venlafaxine (Effexor®).

Consider utilizing a calendar, pillbox, alarm clock, or cell phone alert that will help you keep in mind to take your medicine. You might also ask a member of the family or a buddy to remind you or test in with you to make sure you take your medicine.

What Happens If I Miss A Dose?

If you miss a dose of Venlafaxine take it as quickly as you keep in mind, except it’s nearer to the time of your subsequent dose. Discuss this along with your well being care supplier. Do not double your subsequent dose or take greater than what’s prescribed.

What Should I Avoid While Taking Venlafaxine?

Avoid ingesting alcohol or utilizing unlawful medication while you’re taking antidepressant drugs. They might lower the advantages (e.g., worsen your situation) and improve antagonistic results (e.g., sedation) of the medicine.

What Happens If I Overdose?

If an overdose happens, name your physician or emergency number. You may have pressing medical care. You might also contact the poison management heart. A particular remedy to reverse the consequences doesn’t exist.

What Are Possible Venlafaxine Side Effects?

• Headache
• nausea
• vomiting
• diarrhea,
• constipation
• dry mouth
• elevated sweating
• decreased urge for food
• tremor
• feeling nervous
• stressed
• fatigue
• having bother sleeping (insomnia).
• Sexual unintended effects, reminiscent of issues with orgasm or ejaculatory delay, and blood strain will increase typically don’t enhance over time.
• Increased coronary heart charge
• low blood strain
• elevated salivation
• irregular menstrual cycle
• elevated frequency of urination
• modifications in style
• elevated liver enzymes
• low sodium (signs of low sodium ranges might embrace headache, weak spot, problem concentrating and remembering)
• tooth grinding
• problem urinating
• angle closure glaucoma (signs of angle closure glaucoma might embrace eye ache, modifications in imaginative and prescient, swelling or redness in or round eye)
• serotonin syndrome (signs might embrace shivering, diarrhea, confusion, extreme muscle tightness, fever, seizures, and demise)
• hypertensive disaster (severely elevated blood strain)
• myocardial infarction (coronary heart assault)
• Stevens-Johnson syndrome (rash)

Are There Any Risks For Taking?

To date, there are not any identified issues related to long run use of venlafaxine. It is a protected and efficient medicine when used as directed.

What Other Medications May Interact with Venlafaxine?

Venlafaxine shouldn’t be taken with or inside 2 weeks of taking monoamine oxidase inhibitors (MAOIs). These embrace:

• phenelzine (Nardil®)
• tranylcypromine (Parnate®)
• isocarboxazid (Marplan®)
• rasagiline (Azilect®)
• selegiline (Emsam®)

Although uncommon, there may be an elevated threat of serotonin syndrome when venlafaxine is used with different drugs that improve serotonin, reminiscent of different antidepressants, migraine drugs referred to as “triptans” (e.g., Imitrex®), some ache drugs (e.g., tramadol (Ultram®), the antibiotic linezolid (Zyvox®), and amphetamines.

The following medicine might improve the degrees and results of venlafaxine: ketoconazole (Nizoral®).
Venlafaxine might improve the consequences of different drugs that may trigger bleeding (e.g., ibuprofen (Advil®, Motrin®), warfarin (Coumadin®) and aspirin).

How Long Does It Take For To Work?

Sleep, vitality, or urge for food might present some enhancement throughout the first 1-2 weeks. Improvement in these bodily signs could be an essential early sign that the medicine is working. Depressed temper and lack of curiosity in actions may have as much as 6-8 weeks to totally enhance.