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Carbamazepine Brand names:

• Tegretol® Tablet: 200 mg, 400 mg; Chewable pill: 100 mg; Oral suspension: 100 mg/5 mL
• Tegretol XR® Extended launch pill: 100 mg, 200 mg, 400 mg
• Carbatrol®, Equetro®; Extended launch capsule: 100 mg, 200 mg, 300 mg
• Epitol® Tablet: 200 mg

What is Tegretol?

Tegretol is a temper stabilizer medicine that works within the mind. It is authorized for the remedy of bipolar 1 dysfunction (often known as manic despair) in addition to for epilepsy and trigeminal neuralgia. Bipolar dysfunction entails episodes of despair and/or mania.

Symptoms of despair embrace:

• Depressed temper — feeling unhappy, empty, or tearful
• Feeling nugatory, responsible, hopeless, or helpless
• Loss of curiosity or pleasure in regular actions
• Sleep and eat kind of than common (for most individuals it’s much less)
• Low vitality, bother concentrating, or ideas of demise (suicidal pondering)
• Psychomotor agitation (‘nervous energy’)
• Psychomotor retardation (feeling like you’re transferring in gradual movement)

Symptoms of mania embrace:

• Feeling irritable or “high”
• Having elevated self worth
• Feeling such as you don’t have to sleep
• Feeling the necessity to proceed to speak
• Feeling like your ideas are too fast (racing ideas)
• Feeling distracted
• Getting concerned in actions which can be dangerous or may have dangerous penalties (e.g., extreme spending)

Tegretol might also be useful when prescribed “off-label” for behavioral or psychological signs of dementia. “Off-label” signifies that it hasn’t been authorized by the Food and Drug Administration for this situation. Your psychological well being supplier ought to justify his or her pondering in recommending an “off-label” remedy. They ought to be clear in regards to the limits of the analysis round that medicine and if there are some other choices.

What Is Important Information to know about This medicine?

Bipolar dysfunction requires long-term remedy. Do not cease taking Tegretol, even whenever you really feel higher. With enter from you, your well being care supplier will assess how lengthy you will have to take the drugs. Missing doses of Tegretol might improve your threat for a relapse in your temper signs.

Do not cease taking Tegretol or change your dose with out speaking to along with your healthcare supplier first.

In order for carbamazepine to work correctly, it ought to be taken day-after-day as ordered by your healthcare supplier.

Periodically, your healthcare supplier might ask you to offer a blood pattern to verify the suitable degree of medicine is in your physique and to evaluate for unintended effects, reminiscent of modifications in blood cell counts.

Are There Specific Concerns About Carbamazepine?

If you’re planning on changing into pregnant, notify your healthcare supplier in order that he/she will be able to greatest handle your drugs. People residing with bipolar dysfunction who want to turn out to be pregnant face essential choices. It is essential to debate the dangers and advantages of remedy along with your physician and caregivers.

Carbamazepine has been related to and elevated threat of defects of the top and face, fingernails, and developmental delay. There could also be precautions to lower the chance of this impact. Do not cease taking carbamazepine with out first chatting with your healthcare supplier. Discontinuing temper stabilizer drugs throughout being pregnant has been related to a major improve in symptom relapse.

Regarding breast-feeding, warning is suggested since carbamazepine does move into breast milk. Talk along with your physician about whether or not or not it’s protected to breastfeed whereas taking carbamazepine.

What Should I Discuss With My Healthcare Provider Before Taking Tegretol?

• Symptoms of your situation that trouble you probably the most
• If you’ve gotten ideas of suicide or harming your self
• Medications you’ve gotten taken up to now in your situation, whether or not they had been efficient or induced any antagonistic results
• If you expertise unintended effects out of your drugs, talk about them along with your supplier. Some unintended effects might move with time, however others might require modifications within the medicine.
• Any different psychiatric or medical issues you’ve gotten
• All different drugs you’re at present taking (together with over-the-counter merchandise, natural and dietary dietary supplements) and any medicine allergic reactions you’ve gotten
• Other non-medication remedy you’re receiving, reminiscent of speak remedy or substance abuse remedy. Your supplier can clarify how these totally different therapies work with the medicine.
• If you’re pregnant, plan to turn out to be pregnant, or are breast-feeding
• If you drink alcohol or use unlawful medication

How Should I Take Carbamazepine?

• Carbamazepine is often taken 2-4 occasions per day with or with out meals.
• Typically sufferers start at a low dose of medication and the dose is elevated slowly over a number of weeks.
• The dose often ranges from 200 mg to 1600 mg every day, however some sufferers might require extra primarily based on signs. Only your healthcare supplier can decide the right dose for you.
• Carbamazepine suspension: Measure with a dosing spoon or oral syringe, which you will get out of your pharmacy.
• Extended-release capsules: Swallow complete or sprinkle onto meals, reminiscent of applesauce or pudding and eat instantly. Do not chew the sprinkle capsule or contents.

Use a calendar, pillbox, alarm clock, or cell phone alert that will help you keep in mind to take your medicine. You might also ask a member of the family or a buddy to remind you or test in with you to make sure you take your medicine.

What Happens If I Miss A Dose Tegretol?

If you miss a dose of Tegretol, take it as quickly as you keep in mind, except it’s nearer to the time of your subsequent dose. Discuss this along with your healthcare supplier. Do not double your dose or take greater than what’s prescribed.

What Should I Avoid While Taking Carbamazepine?

Avoid ingesting alcohol or utilizing unlawful medication while you’re taking Tegretol. They might lower the advantages (e.g., worsen your situation) and improve antagonistic results (e.g., sedation) of the medicine.

Avoid consuming giant portions (8 ounces or extra) of recent grapefruit juice, as this will improve ranges of Tegretol and improve your threat of unintended effects or rash.

What Happens If I Overdose?

If an overdose happens name your physician or the emergency number in your local area. You may have pressing medical care. You might also contact the poison management heart.

A particular remedy to reverse the consequences of carbamazepine doesn’t exist.

What Are Possible Carbamazepine Side Effects?

 

• Dizziness or drowsiness
• Unsteadiness when standing or strolling
• Nausea or vomiting
• Dry mouth
• Constipation
• Blurry or double imaginative and prescient
• Carbamazepine could cause a lower within the physique’s sodium degree. Some indicators of low sodium embrace:
  • nausea
  • tiredness
  • lack of vitality
  • headache
  • confusion
  • extra frequent or extra extreme seizures

• Carbamazepine might trigger uncommon however severe blood issues together with low white blood cell counts. Symptoms might embrace:
  • fever
  • sore throat
  • different infections that come and go or don’t go away
  • simple bruising
  • pink or purple spots in your physique
  • bleeding gums or nostril bleeds
  • extreme fatigue or weak spot.

Your physician will often order blood work to observe for this.

In uncommon circumstances (<1%) a extreme, spreading rash with blistering of the pores and skin in patches over your complete physique together with fever, headache and cough can happen (Stevens-Johnson syndrome). Although that is uncommon with Tegretol, discontinuation of this medicine is critical. Rare circumstances of extreme allergic reactions have been reported. Symptoms embrace:

• swelling of the face, eyes, lips, or tongue
• problem swallowing or respiratory.

If you expertise any of those unintended effects, you will need to search medical care instantly.

Studies have discovered that people who take antiepileptic drugs together with carbamazepine have suicidal ideas or behaviors as much as twice as typically than people who take placebo (inactive medicine). These ideas or behaviors occurred in roughly 1 in 500 sufferers taking the antiepileptic class of medicines. If you expertise any ideas or impulses to harm your self, you must contact your physician instantly.

Are There Any Risks For Taking?

To date, there are not any identified issues related to long run use of Tegretol. It is a protected and efficient medicine when used as directed.

It is essential to notice that among the unintended effects listed above (notably modifications in blood sodium, rash, and suicidal ideas) might proceed to happen or worsen if you happen to proceed taking the medicine. It is essential to observe up along with your physician for blood work and to contact your physician instantly if you happen to discover any pores and skin rash or modifications in temper or conduct.

What Other Medications May Interact With Tegretol?

The following drugs might improve the extent and results of Tegretol:

• The temper stabilizer and antiseizure medicine valproic acid/divalproex (Depakote®)
• Certain antibiotics, reminiscent of ciprofloxacin (Cipro®), erythromycin (Ery-tab®), clarithrymycin (Biaxin®)
• Medications for heartburn or reflux, reminiscent of cimetidine (Tagamet®) and omeprazole (Prilosec®)
• Antifungal drugs, reminiscent of ketoconazole (Nizoral®), fluconazole (Diflucan®), itraconazole (Sporanox®), voriconazole (Vfend®)
• Certain coronary heart drugs, reminiscent of diltiazem (Cardizem®) or verapamil (Calan®, Isoptin®)
• Certain drugs used for temper or sleep, reminiscent of trazodone (Desyrel®) or nefazodone (Serzone®)

The following drugs might lower the extent and impact of carbamazepine:

• Phenytoin (Dilantin®), phenobarbital, primidone (Mysoline®)
• Rifampin (Rifadin®)

Carbamazepine might lower the extent and results of:

• Oral contraceptives (contraception tablets)
• Certain drugs used for psychiatric issues, reminiscent of lurasidone (Latuda®), aripiprazole (Abilify®), alprazolam (Xanax®), escitalopram (Lexapro®), trazodone (Desyrel®), and nefazodone (Serzone®)
• Certain coronary heart drugs, reminiscent of diltiazem (Cardizem®) or verapamil (Calan®, Isoptin®)
• Anti-rejection drugs utilized in organ transplants, like tacrolimus (Prograf®) and cyclosporine (Neoral®, Sandimmune®)
• Certain ldl cholesterol drugs, like simvastatin (Zocor®), atorvastatin (Lipitor®)
• The blood thinner warfarin (Coumadin®)
• Antiseizure drugs like phenytoin (Dilantin®), phenobarbital, and valproic acid/divalproex (Depakote®), lamotrigine (Lamictal®)

How Long Does It Take For To Work?

It is essential to inform your physician how you’re feeling issues are going through the first few weeks after you begin taking carbamazepine. It will in all probability take a number of weeks to see sufficiently big modifications in your signs to resolve if carbamazepine is the correct medicine for you.

Mood stabilizer remedy is mostly wanted lifelong for individuals with bipolar dysfunction. Your physician can greatest talk about the length of remedy you want primarily based in your signs and sickness.