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What is Montelukast

Singulair Drug Uses

Montelukast is used to deal with and stop bronchial asthma. It will lower the signs and the variety of acute bronchial asthma assaults. However, this medication shouldn’t be used to alleviate an bronchial asthma assault that has already began. This medication can also be used to stop exercise-induced bronchoconstriction (EIB) and deal with signs of allergic rhinitis (hay fever), together with seasonal (short-term) or perennial (long-term) allergic rhinitis, comparable to sneezing, runny nostril, itching, or wheezing.

What Should You Discuss To Your Doctor Before Using This Medicine

1. Neuropsychiatric Events: Serious neuropsychiatric (NP) events have been reported with use of Montelukast. These postmarketing reports have been highly variable and included, but were not limited to, agitation, aggressive behavior or hostility, anxiousness, depression, disorientation, disturbance in attention, dream abnormalities, dysphemia (stuttering), hallucinations, insomnia, irritability, memory impairment, obsessive-compulsive symptoms, restlessness, somnambulism, suicidal thoughts and behavior (including suicide), tic, and tremor. NP events have been reported in adult, adolescent, and pediatric patients with and without a previous history of psychiatric disorder. NP events have been reported mostly during Montelukast treatment, but some were reported after Montelukast discontinuation.
   
   
2. Acute Asthma: Montelukast is not indicated for use in the reversal of bronchospasm in acute asthma attacks, including status asthmaticus. Patients should be advised to have appropriate rescue medication available. Therapy with Montelukast can be continued during acute exacerbations of asthma. Patients who have exacerbations of asthma after exercise should have available for rescue a short-acting inhaled β-agonist.
   
   
3. Concomitant Corticosteroid Use: While the dose of inhaled corticosteroid may be reduced gradually under medical supervision, Montelukast should not be abruptly substituted for inhaled or oral corticosteroids.
   
   
4. Aspirin Sensitivity: Patients with known aspirin sensitivity should continue avoidance of aspirin or non-steroidal anti-inflammatory agents while taking Montelukast. Although Montelukast is effective in improving airway function in asthmatics with documented aspirin sensitivity, it has not been shown to truncate bronchoconstrictor response to aspirin and other non-steroidal anti-inflammatory drugs in aspirin-sensitive asthmatic patients.
   
   
5. Eosinophilic Conditions: Patients with asthma on therapy with Montelukast may present with systemic eosinophilia, sometimes presenting with clinical features of vasculitis consistent with Churg-Strauss syndrome, a condition which is often treated with systemic corticosteroid therapy. These events have been sometimes associated with the reduction of oral corticosteroid therapy. Physicians should be alert to eosinophilia, vasculitic rash, worsening pulmonary symptoms, cardiac complications, and/or neuropathy presenting in their patients. A causal association between Montelukast and these underlying conditions has not been established.
   
   
6. Risk In Patients With Phenylketonuria: Montelukast contains aspartame, a source of phenylalanine. Phenylalanine can be harmful to patients with phenylketonuria (PKU). Each 4 mg and 5 mg chewable tablet contains 0.674 mg and 0.842 mg of phenylalanine, respectively. Before prescribing Montelukast to a patient with PKU, consider the combined daily amount of phenylalanine from all sources, including Montelukast.

Montelukast Drug Interactions

Although sure medicines shouldn’t be used collectively in any respect, in different instances two totally different medicines could also be used collectively even when an interplay may happen. In these instances, your physician might need to change the dose, or different precautions could also be mandatory. When you take this medication, it’s particularly vital that your healthcare skilled know if you’re taking any of the medicines listed under. The following interactions have been chosen on the premise of their potential significance and are usually not essentially all-inclusive.

Using this medication with any of the next medicines is normally not really helpful, however could also be required in some instances. If each medicines are prescribed collectively, your physician might change the dose or how typically you utilize one or each of the medicines.

• Dasabuvir
• Leflunomide
• Pixantrone
• Teriflunomide

Other Interactions

Certain medicines shouldn’t be used at or across the time of consuming meals or consuming sure kinds of meals since interactions might happen. Using alcohol or tobacco with sure medicines may trigger conditions to happen. The following interactions have been chosen on the premise of their potential significance and are usually not essentially all-inclusive.

Using this medication with any of the next might trigger an elevated threat of sure uncomfortable side effects however could also be unavoidable in some instances. If used collectively, your physician might change the dose or how typically you utilize this medication, or offer you particular directions about using meals, alcohol, or tobacco.

• Grapefruit Juice

Other Medical Problems Singulair

The presence of different medical issues might have an effect on using this medication. Make certain you inform your physician if in case you have every other medical issues, particularly:

• Allergy to aspirin 
• Allergy to nonsteroidal anti-inflammatory medicine (NSAIDs)
• Asthma assault
• Depression
• Mental well being issues
• Phenylketonuria (PKU)

Proper Usage of Montelukast

Use this medication solely as directed by your physician. Do not use extra of it and don’t use it extra typically, until in any other case directed by your physician. This medication comes with a affected person info insert. Read and observe the directions within the insert rigorously. Ask your physician if in case you have any questions.

Montelukast is used to stop bronchial asthma assaults. It shouldn’t be used to alleviate an assault that has already began. For aid of an bronchial asthma assault that has already began, you need to use one other inhaled medication. If you wouldn’t have an inhaled medication to make use of for an assault, or if in case you have any questions on this, examine along with your physician.

To work correctly, montelukast should be taken on the similar time every day, even when your bronchial asthma appears higher. You might take this medication with or with out meals.

For sufferers taking the oral granules:

• Open the packet till you might be prepared to make use of it.
• The oral granules might both be swallowed entire, or dissolved in 1 teaspoonful (5 mL) of chilly or room temperature child system or breast milk, or blended with a spoonful of sentimental meals, comparable to applesauce, carrots, rice, or ice cream. The oral granules shouldn’t be chewed. Do not combine this medication with every other liquid aside from child system or breast milk.
• The blended medication should be given inside quarter-hour and should not be saved for future use.

Montelukast Dosage

The dose of this medication can be totally different for various sufferers. Follow your physician’s orders or the instructions on the label. The following info consists of solely the common doses of this medication. If your dose is totally different, don’t change it until your physician tells you to take action.

The quantity of medication that you simply take will depend on the energy of the medication. Also, the variety of doses you are taking every day, the time allowed between doses, and the size of time you are taking the medication rely on the medical drawback for which you might be utilizing the medication.

• For remedy and prevention of bronchial asthma:
  • For oral dosage kind (tablets):
    • Adults and kids 15 years of age and older: 10 milligrams (mg) as soon as a day within the night.
    • Children youthful than 15 years of age: Use and dose should be decided by your physician.
  • For oral dosage kind (chewable tablets):
    • Children 6 to 14 years of age: 5 milligrams (mg) as soon as a day within the night.
    • Children 2 to five years of age: 4 mg as soon as a day within the night.
    • Children youthful than 2 years of age: Use and dose should be decided by your physician.
  • For oral dosage kind (granules):
    • Children 2 to five years of age: 4 milligrams (mg) (one packet) as soon as a day within the night.
    • Children 12 to 23 months of age: 4 mg (one packet) as soon as a day within the night.
    • Children youthful than 12 months of age: Use and dose should be decided by your physician.
• For prevention of exercise-induced bronchoconstriction:
  • For oral dosage kind (tablets):
    • Adults and kids 15 years of age and older: 10 milligrams (mg) at the very least 2 hours earlier than train. Do not take a second dose inside 24 hours of your common dose.
    • Children youthful than 15 years of age: Use and dose should be decided by your physician.
  • For oral dosage kind (chewable tablets):
    • Children 6 to 14 years of age: 5 milligrams (mg) at the very least 2 hours earlier than train. Do not take a second dose inside 24 hours of your common dose.
    • Children youthful than 6 years of age: Use and dose should be decided by your physician.
• For perennial allergic rhinitis:
  • For oral dosage kind (tablets):
    • Adults 15 years of age and older: 10 milligrams (mg) as soon as a day within the night.
    • Children youthful than 15 years of age: Use and dose should be decided by your physician.
  • For oral dosage kind (chewable tablets):
    • Children 6 to 14 years of age: 5 milligrams (mg) as soon as a day within the night.
    • Children 2 to five years of age: 4 mg as soon as a day within the night.
    • Children youthful than 2 years of age: Use and dose should be decided by your physician.
  • For oral dosage kind (granules):
    • Children 2 to five years of age: 4 milligrams (mg) (one packet) as soon as a day within the night.
    • Children 6 months to 23 months of age: 4 mg (one packet) as soon as a day within the night.
    • Children youthful than 6 months of age: Use and dose should be decided by your physician.
• For seasonal allergic rhinitis:
  • For oral dosage kind (tablets):
    • Adults and kids 15 years of age and older: 10 milligrams (mg) as soon as a day, taken within the morning or night.
    • Children youthful than 15 years of age: Use and dose should be decided by your physician.
  • For oral dosage kind (chewable tablets):
    • Children 6 to 14 years of age: 5 milligrams (mg) as soon as a day, taken within the morning or night.
    • Children 2 to five years of age: 4 mg as soon as a day, taken within the morning or night.
    • Children youthful than 2 years of age: Use and dose should be decided by your physician.
  • For oral dosage kind (granules):
    • Children 2 to five years of age: 4 milligrams (mg) (one packet) as soon as a day, taken within the morning or night.
    • Children youthful than 2 years of age: Use and dose should be decided by your physician.

Missed Dosage

If you miss a dose of this medication, skip the missed dose and return to your common dosing schedule. Do not double doses.

Singulair Storage

• Keep out of the attain of youngsters.
• Do not preserve outdated medication or medication now not wanted.
• Ask your healthcare skilled how you need to eliminate any medication you don’t use.
• Store the medication in a closed container at room temperature, away from warmth, moisture, and direct gentle. Keep from freezing.
• Store the chewable tablets, oral granules, and tablets in its unique package deal or container.

Montelukast Precautions

If you can be taking this medication for a very long time, it is extremely vital that your physician examine you or your little one at common visits. This will enable your physician to see if the medication is working correctly and to examine for any negative effects.

You could also be taking different medicines for bronchial asthma along with montelukast. Do not cease taking these medicines and don’t cut back the dose, even when your bronchial asthma appears higher, until you or your little one are informed to take action by your physician.

Talk to your physician or get medical care instantly if:

• Your or your kid’s signs don’t enhance after utilizing this medication or in the event that they change into worse.
• Your short-acting inhaler doesn’t appear to be working in addition to ordinary and you could use it extra typically.

Montelukast might trigger some individuals to be agitated, disoriented, irritable, or show different irregular behaviors. It may trigger some individuals to have suicidal ideas and tendencies or to change into extra depressed. Report any uncommon ideas or behaviors that bother you or your little one, particularly if they’re new or worsen shortly. Make certain the physician is aware of if you happen to or your little one have bother sleeping, get upset simply, or begin to act reckless. Also inform the physician if you happen to or your little one have sudden or robust emotions, comparable to:

• feeling nervous
• indignant
• stressed
• violent
• scared

This medication might enhance sure white blood cells (eosinophils) and should trigger Churg-Strauss syndrome (blood vessel illness). This normally happens in sufferers who’ve bronchial asthma or are taking oral steroid medicines that’s being stopped or the dose is being decreased or lowered. Check along with your physician instantly if in case you have a sense of pins and needles, numbness in your arms or legs, flu-like signs, rash, or ache or swelling of the sinuses.

Do not take different medicines until they’ve been mentioned along with your physician. This consists of prescription or nonprescription (over-the-counter [OTC]) medicines and natural or vitamin dietary supplements.

Montelukast Side Effects

Along with its wanted results, a medication might trigger some negative effects. Although not all of those uncomfortable side effects might happen, in the event that they do happen they might want medical consideration.

Check along with your physician instantly if any of the next uncomfortable side effects happen:

• Body aches or ache
• cough
• problem in respiratory
• dryness or soreness of the throat
• fever
• headache
• lack of voice
• ache or tenderness across the eyes and cheekbones

Other negative effects not listed can also happen in some sufferers. If you discover some other results, verify along with your healthcare skilled. Call your physician for medical recommendation about negative effects.

Disclaimer

Information concerning psychotic disorders, included within the review of Montelukast, is used for the informative features exclusively as well as should not be thought-about to alternative to licensed healthcare or referral of the well being treatment distributor.