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Brand names:

• Lexapro® Tablets: 5 mg, 10 mg and 20 mg
• Dexanil® Tablets: 5 mg, 10 mg and 20 mg

Generic title: escitalopram (es sye TAL oh pram)

All FDA black field warnings are on the finish of this truth sheet. Please evaluate earlier than taking this treatment.

What Is Escitalopram And What Does It Treat?

Escitalopram is an antidepressant treatment that works within the mind. It is permitted for the remedy of main depressive dysfunction (MDD) and generalized nervousness dysfunction (GAD).

Symptoms of despair embrace:

• Depressed temper – feeling unhappy, empty, or tearful
• Feeling nugatory, responsible, hopeless, and helpless
• Loss of curiosity or pleasure in your ordinary actions
• Sleep and eat roughly than ordinary (for most individuals it’s much less)
• Low power, hassle concentrating, or ideas of dying (suicidal considering)
• Psychomotor agitation (‘nervous energy’)
• Psychomotor retardation (feeling like you might be shifting and considering in sluggish movement)
• Suicidal ideas or behaviors

Generalized nervousness dysfunction (GAD) happens when an individual experiences extreme nervousness or fear for at the least six months. Other signs embrace:

• Restlessness
• Fatigue (low power, feeling drained on a regular basis)
• Difficulty concentrating
• Irritability
• Muscle rigidity
• Sleep disturbance (issue falling asleep or waking up in the course of the night time)

Escitalopram may be useful when prescribed “off-label” for obsessive compulsive dysfunction (OCD), consuming issues reminiscent of binge consuming dysfunction or bulimia nervosa, panic dysfunction, posttraumatic stress dysfunction (PTSD), and premenstrual dysphoric dysfunction (PMDD). “Off-label” signifies that it hasn’t been permitted by the Food and Drug Administration for this situation. Your psychological well being supplier ought to justify his or her considering in recommending an “off-label” remedy. They must be clear concerning the limits of the analysis round that treatment and if there are some other choices.

What you should know before using Escitalopram?

Do not cease taking escitalopram, even if you really feel higher. With enter from you, your well being care supplier will assess how lengthy you will want to take the drugs.

Missing doses of escitalopram might enhance your threat for relapse in your signs.

Stopping escitalopram abruptly might end in a number of of the next withdrawal signs: irritability, nausea, feeling dizzy, vomiting, nightmares, headache, and/or paresthesias (prickling, tingling sensation on the pores and skin).

Depression can also be part of bipolar sickness. People with bipolar dysfunction who take antidepressants could also be in danger for “switching” from despair into mania. Symptoms of mania embrace “high” or irritable temper, very excessive vanity, decreased want for sleep, stress to maintain speaking, racing ideas, being simply distracted, incessantly concerned in actions with a big threat for unhealthy penalties (for instance, extreme shopping for sprees).

Medical consideration must be sought if serotonin syndrome is suspected. Please check with severe unwanted side effects for indicators/signs.

Are There Specific Concerns About Escitalopram And Pregnancy?

If you might be planning on changing into pregnant, notify your well being care supplier to finest handle your drugs. People dwelling with MDD who want to grow to be pregnant face essential selections. Untreated MDD has dangers to the fetus, in addition to the mom. It is essential to debate the dangers and advantages of remedy together with your physician and caregivers. For ladies who take antidepressant drugs throughout weeks 13 by way of the top of their being pregnant (second and third trimesters), there’s a threat that the child might be born earlier than it’s totally developed (earlier than 37 weeks).

For moms who’ve taken SSRIs throughout their being pregnant, there seems to be lower than a 1% likelihood of infants growing persistent pulmonary hypertension. This is a probably deadly situation that’s related to use of the antidepressant within the second half of being pregnant. However, ladies who discontinued antidepressant remedy had been 5 occasions extra more likely to have a despair relapse than those that continued their antidepressant. If you might be pregnant, please talk about the dangers and advantages of antidepressant use together with your well being care supplier.

Caution is suggested with breastfeeding since escitalopram does go into breast milk.

What Should I discuss with my doctor Before Taking Escitalopram?

• Symptoms of your situation that hassle you essentially the most
• If you’ve got ideas of suicide or harming your self
• Medications you’ve got taken prior to now to your situation, whether or not they had been efficient or triggered any hostile results
• If you expertise unwanted side effects out of your drugs, talk about them together with your supplier. Some unwanted side effects might go with time, however others might require adjustments within the treatment.
• Any different psychiatric or medical issues you’ve got, together with a historical past of bipolar dysfunction
• All different drugs you might be at the moment taking (together with over-the-counter merchandise, natural and dietary dietary supplements) and any treatment allergic reactions you’ve got
• Other non-medication remedy you might be receiving, reminiscent of discuss remedy or substance abuse remedy. Your supplier can clarify how these totally different remedies work with the treatment.
• If you might be pregnant, plan to grow to be pregnant, or are breastfeeding
• If you drink alcohol or use medication

How Should I Take Escitalopram?

Escitalopram is often taken one time per day with or with out meals.

Typically sufferers start at a low dose of drugs and the dose is elevated slowly over a number of weeks.

The dose often ranges from 10 mg to twenty mg. Only your well being care supplier can decide the right dose for you.

The liquid must be measured with a dosing spoon or oral syringe which you may get out of your pharmacy.

Consider utilizing a calendar, pillbox, alarm clock, or mobile phone alert that can assist you keep in mind to take your treatment. You may ask a member of the family or buddy to remind you or verify in with you to make certain you take your treatment.

What Happens If I Miss A Dose Of Escitalopram?

If you miss a dose of escitalopram, take it as quickly as you keep in mind, until it’s nearer to the time of your subsequent dose. Discuss this together with your well being care supplier. Do not double your subsequent dose or take greater than what’s prescribed.

What Should I Avoid While Taking Escitalopram?

Avoid ingesting alcohol or utilizing unlawful medication when you are taking antidepressant drugs. They might lower the advantages (e.g., worsen your situation) and enhance hostile results (e.g., sedation) of the treatment.

What Happens If I Overdose With Escitalopram?

If an overdose happens, name your physician or 911. You may have pressing medical care. You may contact the poison management middle at your local hospital. A selected remedy to reverse the consequences of escitalopram doesn’t exist.

What Are The Possible Side Effects Of Escitalopram?

Common unwanted side effects::

• Headache
• Nausea
• Diarrhea
• Dry mouth
• Elevated sweating
• Feeling nervous
• Stressed
• fatigue, or having hassle sleeping (insomnia)

These will usually enhance over the primary week or two as you proceed to take the treatment.

Sexual unwanted side effects, reminiscent of issues with orgasm or ejaculatory delay usually don’t diminish over time.

Rare/severe unwanted side effects:

• Low sodium blood ranges (signs of low sodium ranges might embrace headache,
• weak point
• issue concentrating and remembering)
• enamel grinding
• angle closure glaucoma (signs of angle closure glaucoma might embrace eye ache,
• adjustments in imaginative and prescient, swelling or redness in or round eye),
• serotonin syndrome (signs might embrace shivering
• diarrhea
• confusion
• extreme muscle tightness
• fever
• seizures, and dying)
• seizure

SSRI antidepressants together with escitalopram might enhance the danger of bleeding occasions. Combined use of aspirin, nonsteroidal anti-inflammatory medication (e.g., ibuprofen, naproxen), warfarin, and different anti-coagulants might enhance this threat. This might embrace signs reminiscent of gums that bleed extra simply, nostril bleed, or gastrointestinal bleeding. Some circumstances have been life threatening.

Are There Any Risks For Taking Escitalopram For Long Periods Of Time?

To date, there aren’t any identified issues related to long run use of escitalopram. It is a secure and efficient treatment when used as directed.

What Other Medications May Interact With Escitalopram?

Escitalopram shouldn’t be taken with or inside 2 weeks of taking monoamine oxidase inhibitors (MAOIs). These embrace phenelzine (Nardil®), tranylcypromine (Parnate®), isocarboxazid (Marplan®), rasagiline (Azilect®), and selegiline (Emsam®).

Although uncommon, there may be an elevated threat of serotonin syndrome when escitalopram is used with different drugs that enhance serotonin, reminiscent of different antidepressants, migraine drugs known as “triptans” (e.g., Imitrex®), some ache drugs (e.g., tramadol (Ultram®), the antibiotic linezolid (Zyvox®), and amphetamines.

Escitalopram might enhance the consequences of different drugs that may trigger bleeding (e.g., ibuprofen (Advil®, Motrin®), warfarin (Coumadin®) and aspirin).

How Long Does It Take For Escitalopram To Work?

Sleep, power, or urge for food might present some enchancment throughout the first 1-2 weeks. Improvement in these bodily signs might be an essential early sign that the treatment is working. Depressed temper and lack of curiosity in actions may have as much as 6-8 weeks to completely enhance.

Summary Warnings

Depression and sure different psychiatric issues are themselves related to will increase within the threat of suicide. Patients with main depressive dysfunction (MDD), each grownup and pediatric, might expertise worsening of their despair and/or the emergence of suicidal ideation and habits (suicidality) or uncommon adjustments in habits, whether or not or not they’re taking antidepressant drugs. This threat might persist till important remission happens.

In short-term research, antidepressants elevated the danger of suicidality in kids, adolescents, and younger adults when in comparison with placebo. Short-term research didn’t present a rise within the threat of suicidality with antidepressants in comparison with placebo in adults past age 24. Adults age 65 and older taking antidepressants have a decreased threat of suicidality. Patients, their households, and caregivers must be alert to the emergence of tension, restlessness, irritability, aggressiveness and insomnia. If these signs emerge, they need to be reported to the affected person’s prescriber or well being care skilled. All sufferers being handled with antidepressants for any indication ought to look ahead to and notify their well being care supplier for worsening signs, suicidality and weird adjustments in habits, particularly throughout the first few months of remedy.