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Active Ingredient: Sumatriptan
Brand(s): Imitrex

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What is Sumatriptan

Sumatriptan is an irregular antipsychotic medicine. Blocks dopamine receptors of CNS as well as conflicts dopamine button in basic gangliya as well as in limbic a component of neoncephalon. It is taken at hypersensitivity, disorders of hemopoietic system (along with in anamnesis), alcoholic as well as harmful psychosis, myasthenia, comas.

Imitrex Drug Uses

Sumatriptan is used to deal with acute migraine complications in adults. It shouldn’t be used to stop migraine complications and isn’t used for cluster complications. Sumatriptan works within the mind to alleviate the ache from migraine complications. It belongs to the group of medicines known as triptans.

Many individuals discover that their complications go away utterly after they take sumatriptan. Other individuals discover that their complications are a lot much less painful, and that they can return to their regular actions though their complications are usually not utterly gone. Sumatriptan typically relieves different signs that happen along with a migraine headache, comparable to nausea, vomiting, sensitivity to gentle, and sensitivity to sound.

Sumatriptan shouldn’t be an peculiar ache reliever. It is not going to relieve ache aside from from migraine complications. This medication is normally used for individuals whose complications are usually not relieved by acetaminophen, aspirin, or different ache relievers.

Sumatriptan has brought on critical uncomfortable side effects in some individuals, particularly individuals who have coronary heart or blood vessel illness. Be certain that you simply talk about along with your physician the dangers of utilizing this medication in addition to the advantages that it may well have.

What Should You Discuss To Your Doctor Before Using This Medicine

In deciding to make use of a medication, the dangers of taking the medication should be weighed towards the nice it’s going to do. This is a choice you and your physician will make. For this medication, the next needs to be thought of:

  1. Arrhythmias: Life-threatening disturbances of cardiac rhythm, including ventricular tachycardia and ventricular fibrillation leading to death, have been reported within a few hours following the administration of 5-HT1 agonists. Discontinue IMITREX Injection if these disturbances occur. IMITREX Injection is contraindicated in patients with Wolff-Parkinson-White syndrome or arrhythmias associated with other cardiac accessory conduction pathway disorders.

  2. Chest, Throat, Neck, And/Or Jaw Pain/Tightness/Pressure: Sensations of tightness, pain, pressure, and heaviness in the precordium, throat, neck, and jaw commonly occur after treatment with IMITREX Injection and are usually non-cardiac in origin. However, perform a cardiac evaluation if these patients are at high cardiac risk. The use of IMITREX Injection is contraindicated in patients with CAD and those with Prinzmetal’s variant angina.

  3. Cerebrovascular Events: Cerebral hemorrhage, subarachnoid hemorrhage, and stroke have occurred in patients treated with 5-HT1 agonists, and some have resulted in fatalities. In a number of cases, it appears possible that the cerebrovascular events were primary, the 5-HT1 agonist having been administered in the incorrect belief that the symptoms experienced were a consequence of migraine when they were not. Also, patients with migraine may be at increased risk of certain cerebrovascular events (e.g., stroke, hemorrhage, TIA). Discontinue IMITREX Injection if a cerebrovascular event occurs.

  4. Medication Overuse Headache: Overuse of acute migraine drugs (e.g., ergotamine, triptans, opioids, or combination of these drugs for 10 or more days per month) may lead to exacerbation of headache (medication overuse headache). Medication overuse headache may present as migraine-like daily headaches, or as a marked increase in frequency of migraine attacks. Detoxification of patients, including withdrawal of the overused drugs, and treatment of withdrawal symptoms (which often includes a transient worsening of headache) may be necessary.

  5. Serotonin Syndrome: Serotonin syndrome may occur with IMITREX Injection, particularly during co-administration with selective serotonin reuptake inhibitors (SSRIs), serotonin norepinephrine reuptake inhibitors (SNRIs), tricyclic antidepressants (TCAs), and MAO inhibitors [see DRUG INTERACTIONS]. Serotonin syndrome symptoms may include mental status changes (e.g., agitation, hallucinations, coma), autonomic instability (e.g., tachycardia, labile blood pressure, hyperthermia), neuromuscular aberrations (e.g., hyperreflexia, incoordination), and/or gastrointestinal symptoms (e.g., nausea, vomiting, diarrhea). The onset of symptoms usually occurs within minutes to hours of receiving a new or a greater dose of a serotonergic medication. Discontinue IMITREX Injection if serotonin syndrome is suspected.

Sumatriptan Drug Interactions

Although sure medicines shouldn’t be used collectively in any respect, in different instances two totally different medicines could also be used collectively even when an interplay may happen. In these instances, your physician might need to change the dose, or different precautions could also be mandatory. When taking this medication, it’s particularly vital that your healthcare skilled know if you’re taking any of the medicines listed under. The following interactions have been chosen on the premise of their potential significance and are usually not essentially all-inclusive.

Using this medication with any of the next medicines shouldn’t be really helpful. Your physician might determine to not deal with you with this medicine or change a number of the different medicines you are taking.

  • Almotriptan
  • Bromocriptine
  • Dihydroergotamine
  • Eletriptan
  • Ergoloid Mesylates
  • Ergonovine
  • Ergotamine
  • Frovatriptan
  • Furazolidone
  • Iproniazid
  • Isocarboxazid
  • Linezolid
  • Methylene Blue
  • Methylergonovine
  • Methysergide
  • Moclobemide

Other Interactions

Certain medicines shouldn’t be used at or across the time of consuming meals or consuming sure kinds of meals since interactions might happen. Using alcohol or tobacco with sure medicines may trigger interactions to happen. Discuss along with your healthcare skilled using your medication with meals, alcohol, or tobacco.

Other Medical Problems Imitrex

The presence of different medical issues might have an effect on using this medication. Make certain you inform your physician if in case you have every other medical issues, particularly:

  • Angina (chest ache)
  • Arrhythmia (coronary heart rhythm drawback)
  • Basilar migraine (migraine with imaginative and prescient and listening to issues)
  • Cerebrovascular illness (eg, stroke, transient ischemic assault)
  • Heart assault
  • Heart or blood vessel issues
  • Hemiplegic migraine (migraine with some paralysis)
  • Hypertension (hypertension), uncontrolled or
  • Ischemic bowel illness (bowels have low blood provide)
  • Liver illness
  • Peripheral vascular illness (clogged arteries)
  • Stroke
  • Transient ischemic assault (TIA)
  • Wolff-Parkinson-White Syndrome (coronary heart rhythm drawback): Should not be utilized in sufferers with these situations.
  • Seizures or epilepsy
  • Stomach or intestinal bleeding: Use with warning. May make these situations worse.
  • Coronary artery illness
  • Diabetes
  • Hypercholesterolemia (excessive ldl cholesterol within the blood)
  • Hypertension (hypertension)
  • Liver illness
  • Obesity
  • Raynaud’s syndrome: Use with warning. May be at elevated threat for extra critical uncomfortable side effects.

Proper Usage of Sumatriptan

Do not use this medication for a headache that’s totally different out of your ordinary migraines. Talk to your physician about what to do for normal complications.

  • To relieve your migraine as quickly as attainable, use this medication as quickly because the headache ache begins. Even if you happen to get warning alerts of a coming migraine (an aura), you need to wait till the headache ache begins earlier than utilizing sumatriptan.
  • Ask your physician forward of time about every other medication you may take if sumatriptan doesn’t work. After you utilize the opposite medication, examine along with your physician as quickly as attainable. Headaches that aren’t relieved by sumatriptan are generally attributable to situations that want different remedy.
  • If you are feeling significantly better after a dose of sumatriptan, however your headache comes again or will get worse after some time, wait at the very least 2 hours earlier than taking one other dose. However, use this medication solely as directed by your physician. Do not use extra of it, and don’t use it extra typically, than directed. Using an excessive amount of sumatriptan might enhance the possibility of uncomfortable side effects. Do not take greater than 200 mg in 24 hours.
  • Swallow the pill entire with water or different liquids. Do not crush, break, or chew it.
  • You might take the pill with or with out meals.
  • This medication comes with a affected person info leaflet. Read and observe the directions rigorously. Ask your physician if in case you have any questions.

Sumatriptan Dosage

The dose of this medication can be totally different for various sufferers. Follow your physician’s orders or the instructions on the label. The following info consists of solely the common doses of this medication. If your dose is totally different, don’t change it until your physician tells you to take action.

The quantity of medication that you simply take will depend on the energy of the medication. Also, the variety of doses you are taking every day, the time allowed between doses, and the size of time you are taking the medication rely on the medical drawback for which you might be utilizing the medication.

  • For oral dosage kind (tablets):
    • For migraine complications:
      • Adults: 25, 50, or 100 milligrams (mg) as a single dose. If you get some aid, or if the migraine comes again after being relieved, one other dose could also be taken 2 hours after the final dose. Do not take greater than 200 mg in any 24-hour interval.
      • Children: Use and dose should be decided by your physician.

Missed Dosage

If you miss a dose of this medication, skip the missed dose and return to your common dosing schedule. Do not double doses.

Imitrex Storage

  1. Store the medication in a closed container at room temperature, away from warmth, moisture, and direct gentle. Keep from freezing.
  2. Keep out of the attain of youngsters.
  3. Do not preserve outdated medication or medication now not wanted.
  4. Ask your healthcare skilled how you need to eliminate any medication you don’t use.

Sumatriptan Precautions

It is essential that your physician examine your progress at common visits. This will enable your physician to see if the medication is working correctly and to determine if you happen to ought to proceed to make use of it.

Check along with your physician if you happen to used this medication and it didn’t work. Also, examine along with your physician in case your migraine complications are worse or if they’re occurring extra typically because you began utilizing this medication.

You mustn’t use this medication if in case you have used an MAO inhibitor (MAOI) comparable to phenelzine (Nardil®) or tranylcypromine (Parnate®) inside the previous 2 weeks. Do not use this medication if in case you have taken different triptan migraine medicines or ergot-type medicines inside the previous 24 hours. Some examples of triptan medicines are almotriptan (Axert®), eletriptan (Relpax®), naratriptan (Amerge®), or zolmitriptan (Zomig®). Some examples of ergot-type medicines are dihydroergotamine (D.H.E. 45®, Migranal®), ergotamine (Bellergal®, Cafergot®, Ergomar®, Wigraine®), or methysergide (Sansert®).

This medication might trigger issues if in case you have coronary heart illness. If your physician thinks you might need an issue with this medication, she or he might want you to take your first dose within the physician’s workplace or clinic.

Sumatriptan Side Effects

Along with its wanted results, a medication might trigger some negative effects. Although not all of those uncomfortable side effects might happen, in the event that they do happen they might want medical consideration.

  • Abdominal or abdomen ache
  • anxiousness
  • blurred imaginative and prescient
  • adjustments in patterns and rhythms of speech
  • chest ache or tightness
  • chills
  • confusion
  • dizziness
  • quick, sluggish, irregular, pounding, or racing heartbeat or pulse
  • headache
  • muscle cramps and stiffness
  • neck, throat, or jaw ache
  • nightmares
  • shivering
  • sweating
  • swelling of the fingers, fingers, ft, or decrease legs
  • tightness within the chest
  • bother respiratory

Other negative effects not listed can also happen in some sufferers. If you discover some other results, verify along with your healthcare skilled. Call your physician for medical recommendation about negative effects.


Information concerning psychotic disorders, included within the review of Sumatriptan, is used for the informative features exclusively as well as should not be thought-about to alternative to licensed healthcare or referral of the well being treatment distributor.


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On this website we do not sell any medications and refer visitors to trusted Internet providers. In this way, we save you and the best price to people many problems and you can easily and legally obtain this powerful medicine.

Frequently asked questions

  • What is Sumatriptan Imitrex?

    Sumatriptan is a drug that is used for treating migraine attacks with or without the presence of an aura, to relieve cluster headache attacks. Can relieves headaches and migraines.

  • What to do if you miss a dose?

    If you miss a dose of Sumatriptan, take it as quickly as potential. However, whether it is virtually time to your subsequent dose, skip the missed dose and return to your common dosing schedule. Do not double doses.

  • What if u take too much Imitrex?

    If an overdose happens, name your physician or call your nearest hospital. You might have pressing medical care. You might also contact the poison management at your local hospital.

  • How to store Sumatriptan?

    Store this medication at a temperature of 2-30 C (36-86 F) in a tight container resistant to light and moisture.

  • What Should I Avoid While Taking Sumatriptan?

    Avoid consuming alcohol or utilizing unlawful medicine when you are taking Imitrex. They might lower the advantages (e.g. worsen your confusion) and improve hostile results (e.g. sedation) of the remedy.

  • What are the side effects of Sumatriptan Imitrex?

    This medication is usually well tolerated and adverse reactions are not expected. Most frequent side effects include pain or tightness in the chest or throat, tingling, flushing, weakness, dizziness, abdominal discomfort, sweating, nasal irritation, and injection site reactions. 

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Last Updated on November 9, 2021 by Toni El Clikos

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